This summary covers the issue of May 1, 2008. Featured are articles on hypertension in the very elderly, the shared genetic causes of childhood-onset cardiac hypertrophy, gene mutations and outcomes in cytogenetically normal AML, microRNA expression in cytogenetically normal AML, and a behavioral intervention to improve obstetrical care; a review article on the nonsurgical management of obesity in adults; a Clinical Problem-Solving article entitled "Back to Basics"; and Perspective articles on public opinion and health care and on the FDA, preemption, and the Supreme Court.

This summary covers the issue of April 24, 2008. Featured are articles on stents versus coronary-artery bypass grafting for left main coronary artery disease, home AEDs for sudden cardiac arrest, pyruvate kinase deficiency and malaria, mutations in the iodotyrosine deiodinase gene and hypothyroidism, ezetimibe use in the United States and Canada, and mast cells and pancreatic cancer; a review article on artesunate for severe falciparum malaria; a case report of a man with rheumatoid arthritis and lymphadenopathy; and Perspective articles on trying times at the FDA regarding the safety of imported pharmaceuticals, on playing "Kick the FDA", and on eliminating blinding trachoma.

This summary covers the issue of April 17, 2008. Featured are articles on weekly paclitaxel and breast cancer, intensive care for extremely premature newborns, YKL-40 levels and asthma, pharmaceutical promotion to physicians and first amendment rights, tectonic shifts in the health information economy, electronic health records and medical research, and grassroots activism and physician supply; review articles on the irritable bowel syndrome and on the management of very low birth weight; a case report of a newborn infant with apnea and seizures; and Perspective articles on personally controlled online health data, on avoiding the pitfalls of going electronic, and on the physician workforce crisis.

This summary covers the issue of April 10, 2008. Featured are articles on telmisartan, ramipril, or both in high-risk vascular disease, acyclovir and the incidence of HIV infection among women in Tanzania, long-term results of carotid stenting versus endarterectomy, recent resurgence of mumps in the United States, legal and regulatory issues in medical outsourcing, and activated protein C and diabetic nephropathy; a review article on the challenge of HIV-1 subtype diversity; a case report of man with changes in mental status after liver transplantation; an interactive Clinical Decisions article on the management of carotid stenosis; and Perspective articles on state health care reform and the prospect for national change, on the risks and benefits of individual health insurance mandates, and on challenges to HIV prevention.

This summary covers the issue of March 20, 2008. Featured are articles on the treatment of the hypereosinophilic syndrome with mepolizumab, duration of red-cell storage and complications after cardiac surgery, polymorphisms associated with cholesterol and risk of cardiovascular events, and quality of life and satisfaction with outcome among prostate-cancer survivors; review articles on hormonal contraception in women of older reproductive age and on acinetobacter infection; a case report of a woman with a nonhealing ulcer of the jaw; and Perspective articles on consent for organ donation and on the extension of asthma's global reach.

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